Risk factors for psychosis tend to coincide with risk factors for developing any mental disorder, as they are not very specific. However, there are some that may be related to this disorder:

• A family history of psychotic disorder increases the risk of having it, depending on the degree of kinship of the affected family member.
• Some mental health signs and symptoms that are frequently observed in early childhood can eventually develop into a psychotic disorder, such as neuropsychological alterations (in memory, attention, concentration, etc.), alterations in social cognition (ability to think about one's own and others' mental states); and difficulties in emotional regulation. Some of these may also be attenuated psychotic symptoms (what is known as a high-risk mental state for psychosis).
• The consumption of toxic substances .
• Having been a victim of traumatic experiences in childhood.
• Factors such as environmental stress (stressful living conditions).

However, all of these variables interact with biological risk factors (unspecific neurobiological ones) at the onset of the disorder, and, therefore, none of these factors alone causes a psychotic disorder in a person who does not have this biological vulnerability.