Like all medications, antidepressants can have side effects, which depend on the mechanism of action of each drug. If the person cannot tolerate the adverse effects, a change in treatment may be considered.

Medication should not be stopped without professional supervision. Antidepressants should not be stopped abruptly because withdrawal symptoms (anxiety, diarrhea, vivid dreams) may occur. These effects can be avoided by slowly reducing the dose before stopping completely.

The duration of treatment should be determined by a professional according to each person's clinical condition.